背根神经节影像应用现状及前景

Current Status and Prospects of Imaging Applications of Dorsal Root Ganglia

摘要:

背根神经节(dorsal root ganglion, DRG)在慢性疼痛的发病机理及治疗应用方面有其特点,是近年来疼痛研究热点。针对人体DRG的结构及功能成像,由于其无创、实时、动态,是研究DRG的重要方向。但由于DRG体积小,周边骨质结构复杂,呼吸和脊髓硬膜囊搏动伪差等原因,DRG功能及结构影像应用受到一定限制。本文系统综述了DRG成像领域的最新进展,涵盖DRG现有成像技术及其优势与局限性分析,并探讨了未来DRG影像研究的可能方向,包括多模态成像技术在DRG中的相关应用等,以期为DRG成像技术的深入研究提供指引和参考。

Abstract:

The dorsal root ganglion (DRG) plays a unique role in the pathogenesis and therapeutic applications of chronic pain, making it a focal point of recent pain research. Imaging of the DRG"s structure and function in humans is an important research direction due to its non-invasive, real-time, and dynamic nature. However, the small size of the DRG, complex surrounding bone structures, and artifacts caused by respiratory and spinal dura mater pulsations have limited the application of DRG functional and structural imaging. This article provides a systematic review of the latest advances in DRG imaging, covering existing imaging techniques, their advantages and limitations, and exploring potential future directions for DRG imaging research, including the application of multimodal imaging techniques in DRG, with the aim of providing guidance and reference for further research in DRG imaging technology.