Pain DETECT Questionnaire的汉化、多中心验证及其与 NPQ、ID-pain量表的对比研究*

Validation and Comparison of PD-Q, NPQ, and ID-Pain in Elderly Chinese*

摘要:

目的：完成PD-Q的汉化,并研究其在中国老年神经病理性疼痛病人中的信效度,与NPQ、ID-pain量表对比,探索符合中国老年人群特征的筛查工具。方法：1.按照量表汉化的流程翻译PD-Q。2.由参与本项目的8个医疗机构共选入神经病理性疼痛病人160例,伤害感受性疼痛病人160例,填写中文版PD-Q、ID pain量表、NPQ。分析量表的信度(Cronbach’S Alpha 系数)和效度(ROC 曲线、AUC、敏感度、特异度、阳性预测值和阴性预测值),比较三个量表的 ROC 曲线下面积。结果：PD-Q汉化版具有较好信效度,ID pain量表具有较高敏感度(88.6%),PD-Q具有较高特异度(93.1%),NPQ具有较高ROC曲线下面积(0.943±0.015)。结论：PD-Q汉化版可以作为中国老年神经病理性疼痛的筛查工具,三个量表在评估神经病理性疼痛方面各有优劣,可按需选择。

Abstract:

Objective: To complete the Chinese cross-cultural adaptation of the PainDetect Questionnaire (PD-Q) and evaluate its reliability and validity in elderly Chinese patients with neuropathic pain, while comparing its performance with the Neuropathic Pain Questionnaire (NPQ) and ID-Pain scale to identify optimal screening tools tailored to the geriatric population in China.Methods: 1. The PD-Q was translated and culturally adapted following standardized cross-cultural adaptation guidelines. 2. A total of 320 patients (160 with neuropathic pain and 160 with nociceptive pain) were enrolled from 8 participating medical institutions. All participants completed the Chinese versions of PD-Q, ID-Pain, and NPQ. Reliability was assessed using Cronbach’s α coefficient, while validity was evaluated through ROC curves, AUC values, sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV). The AUC-ROC of the three scales was statistically compared.Results: The Chinese version of PD-Q demonstrated satisfactory reliability and validity. ID-Pain exhibited the highest sensitivity (88.6%), PD-Q showed superior specificity (93.1%), and NPQ achieved the highest AUC-ROC (0.943 ± 0.015).Conclusion: The Chinese-adapted PD-Q is a valid screening tool for neuropathic pain in elderly Chinese patients. Each scale presents distinct strengths (ID-Pain for sensitivity, PD-Q for specificity, NPQ for diagnostic accuracy), enabling tailored selection based on clinical needs.