针刺痛敏穴治疗肌筋膜疼痛综合征的现代研究进展

Modern Research Progress on Acupuncture at Sensitized Acupoints for Myofascial Pain Syndrome

摘要:

肌筋膜疼痛综合征（MPS）是一种常见的慢性疼痛性疾病，成年人群患病率高且多伴功能障碍。针刺作为安全有效的非药物疗法，可显著改善患者疼痛症状及生活质量。当前针刺干预MPS机制研究的综述较少，本文基于穴位敏化理论和MPS病理基础，系统总结针刺痛敏穴的镇痛作用：通过抑制致痛介质（如SP、CGRP）释放调控炎症-免疫应答、修复下行抑制功能以阻断“外周-中枢”敏化级联、协同调节神经传导通路逆转疼痛病理进程，以期为临床精准治疗提供循证依据。

Abstract:

Myofascial pain syndrome (MPS) is a common chronic pain disorder with high prevalence and associated dysfunction in adults. Acupuncture, a safe and effective non-drug therapy, significantly improves pain symptoms and quality of life. Based on the theory of acupoint sensitization and the pathological basis of MPS, this article systematically summarizes the analgesic effects of acupuncture on pain-sensitive acupoints through three key mechanisms: regulating inflammatory-immune responses by inhibiting the release of pain mediators (e.g., SP and CGRP); restoring descending inhibitory function to block the peripheral-central sensitization cascade; and synergistically modulating neural pathways to reverse pathological pain processes. These findings provide an evidence-based foundation for clinical precision treatment.