Abstract:Objective: The objective of this study was to explore the cognitive characteristics of herpes zoster-related pain, vaccination willingness, and pain management actions among Chinese elderly patients with chronic diseases. Methods: The study employed a quota sampling method based on the population proportion of each province in China, resulting in the collection of 1,635 valid questionnaires. These questionnaires encompassed respondents" perception of pain risk, willingness to vaccinate against herpes zoster, and actions to seek medical attention when pain occurs. Results: The results of the study indicated that approximately 61.0% of the respondents had a history of herpes zoster, of which 95.1% reported experiencing moderate to severe pain. Patients with a history of herpes zoster exhibited a higher perceived intensity of associated pain (p < 0.01) and were more likely to be vaccinated (p < 0.001). Furthermore, individuals afflicted with two or more chronic diseases exhibited an elevated perception of the risk associated with herpes zoster-related pain (p < 0.001). The highly cognitive group demonstrated a higher propensity to engage in proactive preventive measures. Conclusion: The middle-aged and elderly population with chronic diseases exhibited a comprehensive awareness of the risk of herpes zoster-related pain. However, notable variations emerged in their consultation and preventive actions. The findings underscore the necessity for customized health education and intervention strategies, tailored to the distinct characteristics of diverse groups, to enhance vaccination and timely consultation rates.