三叉神经半月节电刺激镇痛应用及进展*
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首都医科大学宣武医院功能神经外科

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科技部国家重点研发计划“主动健康和人口老龄化科技应对”重点专项:老年常见神经病理性疼痛的诊 疗和防控技术研究(2022YFC3602200)


Application and progress of gasserian ganglion stimulationJiang Zai-ying, Ni Bing, Du Tao, Huang Yun-jian, Zu Wei, Yang Dou, Zhu Hong-wei
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Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University

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    摘要:

    在典型三叉神经痛之外,面部三叉神经区域其他慢性疼痛仍困扰着众多患者,药物治疗、射频、微血管减压手术等干预效果对大部分患者并不理想。三叉神经半月节电刺激(gasserian ganglion stimulation, GGS)是一种以三叉神经半月节为靶点的电刺激神经调控疗法,随着技术的不断发展,GGS在临床应用将会越来越广泛,但缺乏其镇痛机制探讨,也缺乏标准化的适应症和手术流程。本文针对GGS的治疗原理、适应症、手术路径及今后可能的发展应用前景进行探讨。

    Abstract:

    In addition to typical trigeminal neuralgia, other facial chronic pain in the distribution of the trigeminal nerve is still plaguing many patients. The effects of drug therapy, radiofrequency, microvascular decompression and other interventions are not ideal for most patients. Gasserian ganglion stimulation (GGS) is an electrical stimulation neuromodulation therapy targeting the gasserian ganglion of the trigeminal nerve. With the continuous development of technology, GGS will be more and more widely used in clinical practice, but there is a lack of research on its analgesic mechanism. There is also a lack of standardized indications and surgical procedures. This article discusses the treatment principle, indications, surgical approaches and possible development and application prospects of GGS in the future.

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  • 收稿日期:2024-11-04
  • 最后修改日期:2024-12-04
  • 录用日期:2025-04-01
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