氢吗啡酮PCA治疗难治性带状疱疹性神经痛的临床疗效观察

Clinical efficacy observation of? PCA in the treatment of refractory herpetic neuralgiaZhao Yifan, Jia Yan, Zhang Wenjing, Chen Jianping

摘要:

目的：探讨PCA治疗难治性带状疱疹性神经痛的有效性和安全性。方法：回顾性分析2022年1月-2023年12月就诊的难治性带状疱疹性神经痛患者，采取PCA治疗的患者30例及非PCA治疗的患者30例，对比两者评估入院前（T0）、入院后第二日清晨（T1），入院后第五日清晨（T2），出院时（T3）的视觉模拟评分（Visual Analogue Scale，VAS）、匹兹堡睡眠质量指数 (Pittsburgh sleep quality index, PSQI)、汉密尔顿焦虑量表 (Hamilton anxiety scale, HAMA) ，记录不良反应并分析。结果：PCA组、NPCA治疗后VAS、PSQI、HAMA均明显下降，且PCA组明显优于对照组。结论：入院时辨别难治性带状疱疹的危险因素（老龄、特殊部位、特殊疾病），采用PCA全程介入难治性带状疱疹性神经痛的治疗，在减轻疼痛、改善睡眠、缓解焦虑上要优于传统疗法，临床应用安全有效，值得推广。

Abstract:

Objective: To explore the effectiveness and safety of PCA in the treatment of refractory herpetic neuralgia. Method: Retrospective analysis was conducted on 30 patients with refractory herpetic neuralgia who visited the hospital from January 2022 to December 2023, including 30 patients treated with PCA and 30 patients treated without PCA. Evaluated VAS、PSQI、HAMA before admission (T0), the second day after admission (T1), the fifth day after admission (T2), and at discharge (T3). MA),record and analyze adverse reactions. Result: After PCA group and NPCA treatment, VAS, PSQI, and HAMA were significantly reduced, and the PCA group was better than the control group. Conclusion: Identifying the risk factors for refractory herpes zoster (aging, special areas, special diseases) upon admission and using PCA full course intervention for the treatment of refractory herpes zoster neuralgia is superior to traditional therapy in reducing pain, improving sleep, and alleviating anxiety. Clinical application is safe and effective, and it is worth promoting.