不同模式经颅磁刺激治疗神经病理性疼痛的研究进展*

Application of Different Modes of Transcranial Magnetic Stimulation for Neuropathic Pain (review) *

摘要:

神经病理性疼痛是由于躯体感觉系统的损害或疾病引起的疼痛,其发生机制可能与伤害性感受器敏化、传入神经元异常的异位兴奋性、脊髓后角促伤害感受的易化等有关。经颅磁刺激是一种无创、非侵入性的治疗神经病理性疼痛的手段,可以有效缓解疼痛。本文就经颅磁刺激治疗神经病理性疼痛的可能机制、不同模式的临床应用、安全性等方面进行综述介绍,旨在为进一步研究经颅磁刺激治疗神经病理性疼痛提供参考及理论依据。

Abstract:

Neuropathic pain is pain caused by a lesion or disease of the somatosensory nervous system, and its mechanism may be related to sensitization of injury receptors, abnormal ectopic excitability of afferent neurons, and vulnerability of the posterior horn of the spinal cord to injury perception. Transcranial magnetic stimulation is a noninvasive means of treating neuropathic pain and can effectively relieve pain. In this paper, we review and introduce the possible mechanisms, clinical application of different modalities, and safety of transcranial magnetic stimulation for the treatment of neuropathic pain, aiming to provide reference and theoretical basis for further research on the treatment of neuropathic pain with transcranial magnetic stimulation.