腰交感神经调控监测指标研究进展
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哈尔滨医科大学附属第四医院

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Progress in Monitoring Indices for Lumbar Sympathetic Nerve Modulation
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The Fourth Affiliated Hospital of Harbin Medical University

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    摘要:

    腰交感神经调控技术是指使用物理方法(如射频热凝)或化学药物(如局部麻醉剂或神经毁损剂)作用于腰交感神经节或链以调控(麻醉或灭活或阻断)神经传导功能的技术。如何判断阻滞成功是目前疼痛医师所关注的热点问题。早期,医生使用肢端温度监测来间接测量血流的变化以评估阻滞是否成功,常用方法为温度计、测温探头和红外热成像技术;红外热成像技术较前两者更加可靠。间接监测指标还包括脉搏血氧饱和度、灌注指数以和脉搏传递时间,其中脉搏传递时间可将心脏射血和在肢端测得的血氧饱和度联系起来,极大地提高了监测指标的准确性。不同于间接血流相关性指标,激光多普勒血流测定和激光散斑流图能够直接提供血流速度和分布的详细信息。而非血流相关性指标皮肤电导,则是能够通过反映交感神经系统的兴奋状态,对阻滞结果进行更为准确、迅速的监测。本文综述了各种腰交感神经阻滞成功的监测方法,重点综述直接血流相关性与非血流相关性监测指标,以期为临床选择提供参考。

    Abstract:

    The technique of lumbar sympathetic nerve modulation refers to the use of physical methods (such as radiofrequency thermal ablation) or chemical agents (such as local anesthetics or neurolytic agents) to act on the lumbar sympathetic ganglia or chain in order to modulate (anesthetize, deactivate, or block) nerve conduction function. Determining the success of the blockade is currently a key concern for pain physicians. Initially, peripheral temperature monitoring was used to indirectly measure changes in blood flow to evaluate the success of the block, commonly utilizing thermometers, temperature probes, and infrared thermography. Infrared thermography is more reliable than the others. Indirect blood flow-related indicators also include pulse oximetry, perfusion index, and pulse transit time. Pulse transit time can correlate cardiac ejection with peripheral oxygen, greatly enhancing the accuracy of monitoring indicators. Unlike indirect blood flow-related indicators, laser Doppler flowmetry and laser speckle flowmetry can directly provide detailed information on blood flow velocity and distribution. On the other hand, non-blood flow-related indicator skin conductance can reflect the excitatory state of the sympathetic nervous system, enable more accurate and rapid monitoring of blockade results. This article reviews various monitoring methods for the successful lumbar sympathetic ganglion blockade, with a focus on both direct blood flow-related and non-blood flow-related monitoring indicators, aiming to provide guidance for clinical selection.

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  • 收稿日期:2024-02-20
  • 最后修改日期:2024-03-29
  • 录用日期:2024-09-02
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