脉冲射频联合电针疗法用于带状疱疹后神经痛
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1.山西医科大学麻醉学系;2.山西医科大学第一医院疼痛科

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Pulsed radiofrequency combined with electroacupuncture for postherpetic neuralgia
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1.Department of Anesthesiology,Shanxi Medical University Shanxi Taiyuan;2.Department of pain,Shanxi Medical University First Hospital,Shanxi Taiyuan

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    摘要:

    目的:探究痛点低频电针联合脉冲射频治疗带状疱疹后神经痛(postherpetic neuralgia,PHN)的临床疗效。方法:选取PHN患者60例,分为对照组(A组)和观察组(B组),各30例。A组:脉冲射频治疗;B组:脉冲射频联合低频电针治疗。于治疗前(T0),治疗后1d(T1)、1w(T2)、2w(T3)、4w(T4)和12w(T5)进行疼痛视觉模拟评分(visual analogue scale, VAS)、焦虑自评量表(self rating anxiety scale, SAS)和抑郁自评量表(self rating depression scale, SDS)评估;T0和T1进行红外热成像(infrared thermal imaging ,ITI)(患者疱疹皮损区域与相对应健侧部位的温差?T℃)和心率变异性(heart rate variability, HRV)分析;记录T0和T5镇痛药用量及治疗过程中的不良事件。结果:两组的一般资料及治疗前VAS、SAS、SDS、ITI、HRV和镇痛用药无统计学差异;治疗后B组T3、T4、T5时VAS评分低于A组,T4、T5的SDS、SAS低于A组;B组T1时ITI(?T℃)低于A组,HRV的LF 低于A组,LF/HF较A组接近正常范围(P<0.05);T5时B组镇痛药用量较A组减少(P<0.05)。结论:痛点低频电针疗法可弥补脉冲射频对部分PHN患者外周疼痛疗效不佳的缺点,同时可改善患者焦虑、抑郁等痛情绪。

    Abstract:

    objective: to explore the clinical efficacy of pain-point low-frequency electroacupuncture therapy combined with pulsed radiofrequency in the treatment of postherpetic neuralgia (PHN). Methods: Sixty patients with PHN were selected and divided into a control group (Group A) and an observation group (Group B) of 30 cases each. Group A: pulsed radiofrequency treatment; Group B: low-frequency electroacupuncture combined with pulsed radiofrequency treatment. Visual analogue scale (VAS), self-rating anxiety scale (SAS) and self-rating depression scale (SDS) were performed before (T0), 1d (T1), 1w (T2), 2w (T3), 4w (T4) and 12w (T5) of treatment. self-rating anxiety scale (SAS) and self-rating depression scale (SDS); infrared thermal imaging (ITI) (temperature difference ?T°C between the patient"s herpes lesion area and the corresponding healthy area) was performed at T0 and T1 and heart rate variability (HRV) was analysed; T0 and T5 analgesic dosage and adverse events during treatment were recorded. results:There were no statistical differences in the general data and pre-treatment VAS, SAS, SDS, ITI, HRV and analgesic medication between the two groups (P > 0.05); after treatment, the VAS scores of Group B were lower than those of Group A at T3, T4, and T5, and the SDS and SAS of T4 and T5 were lower than those of Group A. The ITI (?T℃) of Group B was lower than that of Group A at T1, and the LF of HRV was lower than that of Group A. The LF/HF was closer to the normal range than Group A (P < 0.05); the dosage of analgesic drugs of Group B was reduced compared with that of Group A at T5 (P < 0.05). close to the normal range (P < 0.05); at T5, the dosage of analgesics in Group B was reduced compared with Group A (P < 0.05). conclusion: Pain point low-frequency electroacupuncture therapy can make up for the poor efficacy of pulsed radiofrequency on peripheral pain in some PHN patients, and at the same time can improve the patient"s anxiety, depression and other painful emotions.

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  • 收稿日期:2024-01-19
  • 最后修改日期:2024-03-19
  • 录用日期:2024-09-02
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