Abstract:Objective: The aim of this study was to evaluate the effects of the combination of suprascapular nerve block (SSNB) and axillary nerve block on pain, shoulder range of motion (ROM), disability, and quality of life in the management of patients with adhesive capsulitis. Methods: A total of 100 patients from January 2022 to December 2022 who were diagnosed with adhesive capsulitis were randomly assigned to two groups: SSAX group received SSNB and axillary nerve block combination, while control group only-SSNB. The Shoulder Pain and Disability Index (SPADI),Visual analog scored(VAS), passive shoulder ROMs and the Short Form 36(SF-36) were assessed at baseline and one week,two weeks, one month,three months, and twelve months. The VAS and shoulder ROMs were also examined in the half-hour. Results:Fifty patients? were included in each group .Within the groups, SPADI and VAS scores were decreased, while passive ROMs and the SF-36 scores were increased by time (P < 0.05). Between the groups, the change in VAS value and passive flexion、abduction and external rotation in the half-hour was more remarkable in SSAX group (P < 0.05). No significant difference between outcome measurements was found at the 3rd month (P > 0.05). Conclusion:The combination of suprascapular nerve block and axillary nerve block(SSAX) in the treatment of adhesive shoulder arthritis can significantly improve the patient’s joint function, improve the range of motion and relieve pain,it has positively affected the immediate pain relief and functional improvement after the intervention.