短时程脊髓电刺激预防老年带状疱疹后神经痛的临床观察研究

Prevention of postherpetic neuralgia in the elderly by short-term spinal cord stimulation

摘要:

目的：探究短时程脊髓电刺激治疗老年带状疱疹性疼痛及预防带状疱疹后神经痛的疗效。方法：选取2020年8月至2022年11月于中日友好医院疼痛科就诊的患者200例。使用随机数字表法分为药物治疗组(M组)和短时程脊髓电刺激治疗组(S组),M组给予常规药物治疗,S组给予短时程脊髓电刺激治疗,观察两组患者的疼痛、睡眠、生活质量变化、并发症与疾病转归情况。结果：最终共纳入患者168例,两组患者的疼痛、睡眠及生活质量均较治疗前改善(P <0.001),且S组改善更加明显(P <0.05)。治疗3个月后,S组PHN的发生率低于M组(P <0.05)。结论：短时程脊髓电刺激可以改善老年带状疱疹性神经痛且对PHN的发生具有一定的预防作用。

Abstract:

Objective: To explore the efficacy of short-term spinal cord stimulation in the treatment of elderly herpes zoster pain and the prevention of postherpetic neuralgia. Method: 200 patients who visited the Pain Department of China-Japanese Friendship Hospital from August 2020 to November 2022 were selected. The patients were divided into a medication treatment group (M group) and a short-term spinal cord stimulation treatment group (S group) by the random number table. M group was given routine medication treatment, while S group received short-term spinal cord stimulation treatment. The pain, sleep, quality of life, complications, and incidence rate of PHN in two groups were observed. Result: A total of 168 patients were ultimately included. The pain, sleep, and quality of life in both groups improved compared to before treatment (P<0.001), while the improvement in group S was more significant (P<0.05). After 3 months of treatment, the incidence of PHN in S group was lower than that in S group (P<0.05). Conclusion: Short-term spinal cord stimulation can improve elderly herpes zoster neuralgia and has a preventive effect on the occurrence of PHN.