Abstract:Subjective: To reduce the risk of complications such as pneumothorax and spinal cord injury during thoracic intervertebral foramen puncture, based on CT image measurement, the differences of different genders, ages, and BMI patients were analyzed, and the overall change law of different segments were explored. Methods: 180 adult inpatient chest CT images from the China-Japan Friendship Hospital image database were selected, with the left T2-T12 intervertebral foramen(IF) as the puncture target. CT cross-sectional images that clearly showed the IF were selected, and the puncture operation was simulated. The side distance, angle of needle insertion, depth of needle insertion, and distance from the IF to the posterior median line were measured and analyzed for different genders (male and female), ages (youth, middle age, and old age), and BMI (non-overweight and overweight). The CT images measurement values were expressed as mean ± standard deviation (x ± SD) and analyzed using SPSS 26.0 statistic software. Intergroup comparisons were made using one-way ANOVA analysis, and P <0.05 was considered statistically significant. Results: The side distance and depth of needle insertion of male patients were significantly higher than those of female patients in all thoracic segments (P < 0.01), and the angle of needle insertion of female patients was higher than those of male patients in the upper thoracic segment (P < 0.05). The minimum side distance of old patients in T2-3~T4-5 segments was higher than those of youth and middle age patients (P < 0.05), and the angle of needle insertion in T3-4 and T4-5 segments was smaller than those of youth and middle-aged patients (P < 0.05). The side distance, depth, and angle of needle insertion of overweight patients were higher than those of non-overweight patients in all thoracic segments (P < 0.01), and the angle of needle insertion in T9-10 segment and above was smaller than those of non-overweight patients (P < 0.01). The distance from IF to the posterior median line was the shortest in T5-6 and T6-7, and the distance from the IF to the posterior median line of male patients was significantly higher than that of female patients. The side distance, angle and depth of needle insertion, and distance from the IF to the posterior median line reached a maximum in the middle thoracic segments and gradually decreased or increased to both sides. Conclusion: The side distance, angle, and depth of needle insertion, and distance from the IF to the posterior median line have specific change laws from T2-3 to T11-12, and there are statistical differences in CT image measurement values among different gender, age, and BMI patients, This has particular reference value for the clinical operation of different segments and populations.