Abstract:Abstract Objective: To summarize the perioperative nursing methods of CT-guided percutaneous thoracic sympathetic radiofrequency thermocoagulation combined with absolute ethanol injection in the treatment of primary palmar hyperhidrosis. Methods: The clinical data of 40 patients with primary palmar hyperhidrosis who underwent CT-guided percutaneous thoracic sympathetic radiofrequency thermocoagulation combined with absolute ethanol injection from May 1,2020 to April 30,2021 were retrospectively summarized and analyzed. Results: 40 patients were successfully completed surgery, of which 37 cases of symptomatic relief, 2 cases of PPH classified as mild, 1 case of moderate ; the mean temperature of palm skin increased from 33.09 ± 0.42 °C to 35.92 ± 0.39 °C, and the perfusion index ( PI ) of finger increased from 0.91 ± 0.11 to 4.79 ± 0.54 ( P < 0.001 ). There were 1 case of chest tightness, 8 cases of chest and back pain, 3 cases of compensatory hyperhidrosis and 1 case of Horner syndrome after operation, and the symptoms were relieved after timely and effective treatment. HADS anxiety score, HADS depression score, PSQI sleep score and satisfaction score were significantly improved after nursing. Conclusion : Preoperative disease assessment, psychological care, improve the relevant preoperative preparation ; intraoperative surgical cooperation ; postoperative close observation of the patient 's condition, good wound care, pain care management, complication prevention and discharge guidance can effectively ensure the surgical effect, so that patients can get better recovery and improve their medical experience.