MiR-29b参与了大鼠膝骨关节炎引起的软骨退变和股四头肌萎缩

MiR-29b is Involved in Cartilage Autophagy and Muscle Atrophy resulting from Knee Osteoarthritis in RatsXIE Xiao-ting1 ,ZHENG Yong-jun*

摘要:

目的：初步探讨miR-29b在KOA大鼠股四头肌和关节软骨中的含量表达变化,以及miR-29b antagomir在改善KOA大鼠股四头肌和关节软骨病理变化中的作用,并探究其具体发生机制。

Abstract:

1. To detect the changes of miR-29b in quadriceps and articular cartilage in rat knee osteoarthritis (knee osteoarthritis, KOA) model, and to explore the relationship between miR-29b and muscle atrophy and cartilage degeneration.