Abstract:High-intensity focused ultrasound (HIFU) as a non-invasive ultrasound treatment technology has gradually emerged in recent years. MR-guided HIFU (MRgHIFU) can achieve precise ablation of target tissue, and its temperature measurement function can also real-time monitor the temperature of the ablation zone. These advantages of MRgHIFU enable it to treat lesions accurately while greatly reducing the risk of damage to surrounding tissues, showing good effectiveness and safety. MRgHIFU, as a multi-modal treatment option for different disease states, has been widely used in clinical and preclinical studies in many academic fields such as oncology, nervous system, plastic surgery and rehabilitation medicine. Chronic pain is a major contributor to the global economic and disease burden, in which the spinal and osteoarticular pain is one of the important causes of body dysfunction. As an important non-invasive treatment method, MRgHIFU may play a pivotal role in the comprehensive treatment of spinal and osteoarticular pain. This article reviews the relevant research progress.
