Abstract:Abstract Objective:To investigate the efficacy and safety of ultrasound-guided saphenous nerve pulsed radiofrequency combined with knee joint injection for knee osteoarthritis.Methods:Sixty-two patients with knee osteoarthritis in the pain department of Fangshan Hospital Beijing University of Chinese Medicine from March 2019 to March 2021 were selected.The patients were randomly divieded into the trial group (n=31) and the control group (n=31) according to the visiting sequence.Patients of the trial group were treated with ultrasound-guided saphenous nerve pulsed radiofrequency combined with knee joint injection while patients of the control group were treated with trigger point injection combined with knee joint injection.The VAS score and Lysholm score of the two groups before treatment, 1 week, 1 month, 3 months and 6 months after treatment were recorded.The clinical efficacy was evaluated by intra group comparison and inter group comparison.The complications of the two groups were observed after treatmentResults:After the implementation of the two different treatment methods, the VAS score of the two groups decreased and the Lysholm score increased 1 week, 1 month, 3 months and 6 months after treatment. At the same time point after treatment, the VAS score of the trial group was significantly lower than that of the control group, and the Lysholm score was significantly higher than that of the control group. There was significant difference between the two groups (P < 0.05)The pain of knee joint in the two groups after treatment was relieved to varying degrees,and the function was improved.The efficacy of the trial group was better than that of the control group. No complications occurred. Conclusion:The application of ultrasound-guided saphenous nerve pulsed radiofrequency combined with knee joint injection for knee osteoarthritis not only significantly alleviate pain,but also improve the function of knee.It provides a new path for patients with knee osteoarthritis.