周围神经电刺激对三叉神经V1带状疱疹后神经痛疗效分析

THE THERAPEUTIC EFFECT OF PERIPHERAL NERVE STIMULATION ON POSTHERPETIC NEURALGIA OF TRIGEMINAL V1 NERVE

摘要:

目的：比较眶上神经射频热凝（Percutaneous Radiofrequency Thermocoagulation ,PRT）和周围神经电刺激(Peripheral Nerve Stimulation ,PNS)对三叉神经带状疱疹后神经痛(Postherpetic Neuralgia ,PHN)治疗效果。方法：回顾性分析2018年1月至2021年1月我院收治的三叉神经V1支带状疱疹后神经痛患者60例，分为PRT组和PNS组，采用数字评分法（Numerical Rating Scale , NRS）和匹兹堡睡眠质量指数(Pittsburgh Sleep Quality Index ,PSQI)评估两种治疗方法的疗效。结果：两组NRS评分、PSQI评分对比，术前差异无统计学意义，术后1天、术后1周、1月、3月、6月PNS组均低于PRT组，差异有统计学意义；两组术后各时间点NRS 评分、PSQI评分均较术前明显降低，差异有统计学意义。同时经相关性分析得年龄、病程与治疗效果呈负相关。结论：PNS和眶上神经PRT治疗均有效，对于年龄大、病程长的患者可优先选择PNS。

Abstract:

Objective: To compare the therapeutic effects of supraorbital nerve percutaneous radiofrequency thermocoagulation (PRT) and peripheral nerve stimulation (PNS) on postherpetic neuralgia (PHN) of trigeminal nerve. Methods: Retrospective analysis was performed on 60 patients with postherpetic neuralgia from V1 branch of trigeminal nerve admitted to our hospital from January 2018 to January 2021, and they were divided into PRT group and PNS group. The curative effect of the two treatment methods was evaluated by numerical rating scale (NRS) and Pittsburgh sleep quality index (PSQI). RESULTS: Comparison of NRS score and PSQI score between the two groups showed no statistically significant difference before surgery, while 1 day, 1 week, 1 month, 3 months and 6 months after surgery were all lower in the PNS group than in the PRT group, and the difference was statistically significant; The NRS score and PSQI score of the two groups at each time point after operation were significantly lower than those before operation, and the difference was statistically significant. At the same time, the correlation analysis showed that age, course of disease and treatment effect were negatively correlated. Conclusion: Both PNS and PRT of the supraorbital nerve are effective, and PNS is preferred for patients with older age and longer course of disease.