Abstract:Objective: To evaluate the clinical effects and safety of ultrasound-guided nerve root block and pulsed radiofrequency on cervical spondylotic radiculopathy. Methods: A total of 46 patients with cervical spondylotic radiculopathy in department of pain medicine,Peking University Third Hospital from January 2017 to June 2020, underwent ultrasound-guided selective cervical nerve block and pulsed radiofrequency according to involved cervical nerve root segments. Numeric rating scale(NRS) and therapeutic effect was recorded before treatment and 1 week, 4 weeks, 12 weeks and 24 weeks after treatment. The therapeutic effect was evaluated according to Odom criteria. The incidence of adverse reactions was also recorded after treatment. Results: The cervical nerve root was showed clearly in 41 patients, however, 5 patients had to be confirmed by radio frequency therapy device positioning. The percentage of successful rate is 100%. The NRS score of preoperation and 1 week, 4 weeks, 12 weeks, and 24 weeks after treatment was 6.8±1.0, 3.0±0.8, 3.1±0.8, 2.8±0.7 and 2.7±0.8, respectively. Scores of NRS after treatment were significantly lower than those of before treatment ( P<0.01).According to the Odom criteria,the overall excellent and good rates 1 week,4 weeks,12 weeks and 24 weeks after treatment were 89.1%, 80.4%, 80.4% and 76.1% respectively. There was no operation related nerve injury and other complications among all patients. Conclusion: Ultrasound-guided selective cervical nerve root block and pulsed radiofrequency is a safe and effective method for the treatment of patients with cervical spondylotic radiculopathy.