Abstract:Objective:To observe the effects of ultrasound-guided lateral thoracolumbar interfascial plane for postoperative analgesia in multi-level lumbar spine fusion surgery. Methods:A total of 40 patitents with Lumbar disc herniation for multi-level lumbar spine fusion surgery were randomized and divided into the TLIP?????????? group and control group (each group,n=20) from May, 2019 to Dec, 2020 in Tianjin Hospital. The control group received general anesthesia only. The TLIP group received ultrasound-guided lateral thoracolumbar interfascial plane with 20ml 0.4% ropivacaine before general anesthesia. The consumption of propofol, remifetanil and sufentanil and the incidence of emergence delirium after operation were recorded. The resting/coughing VAS score at 1h, 6h, 12h, 24h, 48h postoperatively, the frequency of PCA compressions and rescue analgesic administrations were compared between the two groups. The occurrence of adverse reaction(nausea and vomiting, respiratory depression, dizziness and pruritus) were recorded. Results:Compared with the control group, the consumption of propofol and remifetanil and the incidence of emergence delirium after operation decreased in the TLIP group（p<0.05）,but there was no difference in the consumption of sufentanil between the two groups. Compared with the control group, the resting/coughing VAS score at 1h, 6h, 12h, 24h, 48h postoperatively were significantly lower in the TLIP group（p<0.05）, but the VAS score increased signifricantly at 24h postoperatively compared with 12h after operation in the TLIP group. Compared with the control group, the frequency of PCA compressions , rescue analgesic administrations and the occurrence of adverse reactions were decreased in the TLIP group, but there were no difference in the incidence of respiratory depression, dizziness and pruritus. Conclusions:Ultrasound-guided lateral thoracolumbar interfascial plane can not olny reduce the pain degree and perioperative anesthetics consumption, but also decline the incidence of nausea and vomiting in patients undergoing posterior lumbar fusion surgery. The TLIP should be worthy of clinical promotion.
