细银质针导热松解联合臭氧注射与神经根脉冲射频治疗带状疱疹后神经痛的疗效比较

Comparison of the efficacy of thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency in the treatment of postherpetic neuralgia

摘要:

目的：比较细银质针导热松解联合臭氧注射与神经根脉冲射频治疗带状疱疹后神经痛（Postherpetic Neuralgia，PHN）的疗效。方法：选择中日友好医院疼痛科2018年1月至2019年11月PHN患者80例，随机均分为细银质针导热松解联合臭氧注射组（S组）和神经根脉冲射频组（R组）。观察术前、术后1小时、3个月、6个月的视觉模拟评分(visual analogue scale, VAS)、阿森斯失眠量表（Athens Insomnia Scale,AIS）评分、生活质量指数问卷（QL-index量表）评分和总体疗效。结果：两组患者术前VAS、AIS和QL-index评分无统计学差异（P>0.05），两组术后1小时、3个月、6个月的VAS、AIS评分明显低于，QL-index评分明显高于术前基础值（P＜0.01）。两组术后1小时的VAS、AIS评分无统计学差异（P>0.05），但术后3个月、6个月时S组明显低于R组（P<0.05）。两组QL-index评分和总体有效率在各时间点无统计学差异（P>0.05）。结论：细银质针导热松解联合臭氧注射和神经根脉冲射频均可有效治疗PHN，但细银质针导热松解联合臭氧注射的痊愈率更高。

Abstract:

Objective: To compare the efficacy of thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency in the treatment of postherpetic neuralgia (PHN). Methods: Eighty patients with PHN from January 2018 to November 2019 in the Pain Department of China-Japan Friendship Hospital were selected and randomly equally allocated to thin silver needle heat conduction combined with ozone injection group (Group S ) and nerve root pulsed radiofrequency group (Group R ). Visual analogue scale (VAS), Athens Insomnia Scale (AIS), Quality of Life Index (QL-index) and overall efficacy were observed preoperatively, 1 hour, 3 months and 6 months postoperatively. Results: Preoperative VAS, AIS, and QL-index scores were not statistically different between the two groups (P>0.05), and the VAS and AIS scores were significantly lower, the QL-index score was significantly higher at 1 hour, 3 months, and 6 months postoperatively than the preoperative baseline value (P<0.01). The VAS and AIS scores were not statistically different between the two groups at 1 hour postoperatively (P>0.05), but which in Group S was significantly lower than Group R at 3 and 6 months postoperatively (P<0.05). There were no statistical differences in QL-index score and overall effective rate between the two groups at each time point (P>0.05). Conclusion: Thin silver needle heat conduction combined with ozone injection and nerve root pulsed radiofrequency were both effective in treating PHN, but the former resulted in a higher recovery rate.