高场强脉冲射频治疗糖尿病合并带状疱疹后神经痛*

Effects of high-field pulsed radio frequency on postherpetic neuralgia with diabetes

摘要:

目的：回顾性分析高场强脉冲射频治疗糖尿病合并带状疱疹后神经痛(postherpetic neuralgia, PHN)的临床效果。 方法： 统计2017年6月至2019年6月期间83例PHN经高场强脉冲射频治疗患者，分为糖尿病组(34例)与无糖尿病组（49例），对其治疗前后NRS（ numeric rating scale, NRS）分值（治疗后1周,1月,3月,6月）、治疗后用药情况及睡眠质量评分（quality of sleep，QS）进行回顾性分析。 结果：治疗后随访6月，，共83例完成随访，两组患者高场强脉冲射频治疗前后NRS评分差异有统计学意义(P < 0.05)；与无糖尿病组比较，糖尿病组患者NRS评分在治疗后1周、1月、3月及6月均要较高（P ＜0.05）；治疗后6月时，与无糖尿病组比较，糖尿病组的曲马多使用率较高，两组患者治疗后1周、1月、3月曲马多使用率及治疗后1周、1月、3月及6月加巴喷丁使用率无统计学意义；与无糖尿病组相比，糖尿病组在治疗后6月时的睡眠质量改善明显较差(P <0.05)。 结论：高场强脉冲射频治疗对糖尿病合并PHN患者治疗有效，但效果不如无糖尿病的PHN患者。

Abstract:

Objective A retrospective analysis of the clinical effects of high-field pulsed radiofrequency in treating diabetes complicated with postherpetic neuralgia (PHN). Methods 83 patients with postherpetic neuralgia, from June 2017 to June 2019, were divided into two groups: diabetic group and non-diabetic group. Patients were received high-field pulsed radiofrequency combined drug therapy.The numeric rating scale (NRS) , postoperative medication and the quality of sleep(QS）were calculated at pre-treatment, and 1week, 1 month, 3 months and 6 months of post-treatment in all patients. Results Compared with pre-treatment，the scores of NRS were signi?cantly decreased in both groups (P< 0.05). Follow-up for 6 months, 1 case was lost to follow-up, 83 cases completed follow-up. The improvement of NRS in the diabetic group at 1week, 1 month, 3 months and 6 months after surgery was significantly lower than that of the non-diabetic group (P< 0.05). Compared with the non-diabetic group, the usage rate of medicine was no significantly different from the diabetic group decreased 6 months of post-treatment (P>0.05). The quality of sleep was significantly lower in the non-diabetic group than that in the diabetic group at 6 months after the treatment (P<0.05). Conclusion High-field pulsed radiofrequency treatment is effective for patients with diabetes and PHN, but the effect is not as good as for patients with PHN alone.