Abstract:Abstract Objective: To investigate the short-term clinical efficacy of lumbar nerve radiofrequency in the treatment of degenerative lumbar spondylolisthesis (DLS) with lumbar spinal stenosis(LSS) for elderly patients. Methods: Retrospective analysis of medical data of old patients admitted for DLS with LSS and received lumbar dorsal root ganglion pulsed radiofrequency combined with lumbar dorsal medial branch radiofrequency ablation from September 2014 to December 2019. The score of numeric rating scale (NRS), Oswestry disability idex (ODI) and modified Macnab criteria were compared at different time points. Results: A total of 55 patients were enrolled. Compared with pre-operation, NRS score and ODI score decreased significantly at all time points after surgery. Compared with 1 month after surgery, the NRS score and ODI score increased significantly at 6 month after surgery.The fine rate (excellent and good rates) of 1 month, 3 month and 6 month after operation was 74.5%、70.9% and 65.5% respectively. Conclusion: Targeted lumbar nerve radiofrequency could relieve pain,improve daily functioning and have a good short-term clinical efficacy in elderly patients with DLS combined with LSS.