Abstract:Objective To evaluate the clinical effect of ultrasound-guided peripheral nerve pulse radiofrequency (PR) and peripheral never block (PL) in the treatment of elderly patients with postherpetic neuralgia. Method A total of 79 patients diagnosed with PHN divided into two groups, 59 cases in PL group, 20 cases in PR group were included. Patients in PL group were successfully treated with ultrasound-guided peripheral never block during hospitalization,while patients in PR group were successfully treated with ultrasound-guided peripheral nerve pulse radiofrequency.The therapeutic effects were evaluated using numeric rating score NRS before and after treatment,even on discharge, one week and one month after discharge. The doses of analgesic and anticonvulsant drugs were also evaluated before and after the treatment. result There were no significant differences in the doses of analgesic and anticonvulsant drugs, NRS scores after treatment and at discharged between the two groups, while they at discharged and after treatment in the two groups were significantly lower than those before treatment (P<0.05),NRS score on one week and one month after discharge of PR group was significantly lowerer than that of PL group (P<0.05). Conclusion Ultrasound-guided peripheral nerve pulse radiofrequency and peripheral never block can significantly reduce the dosage of analgesic drugs, reduce pain score, and have no serious complications in the treatment of elderly patients with postherpetic neuralgia. Long-term curative effect of ultrasound-guided peripheral nerve pulse radiofrequency in the treatment of elderly patients with postherpetic neuralgia was better.