Abstract:With the development of neuroimaging, medical imaging technology has been widely used in clinical research. Among them, functional near-infrared spectroscopy (fNIRS), as an emerging technology, is a non-invasive and non-ionizing method for monitoring and imaging cerebral hemodynamics, which can be used to study brain function in human health and pathology. Pain is the fifth vital sign of human, and its central mechanism is still a research hotspot, which is a good carrier for fNIRS research. According to whether the subjects are required to perform corresponding tasks during data collection, fNIRS is divided into resting state and task state. Compared with resting state, task state is more widely used, more time-sensitive, and the design options are diverse, including Single task such as electrical stimulation and temperature stimulation, and multi-task design combining mechanical stimulation and cognition. Based on the continuous deepening of fNIRS research, this article starts with the design of the task state, focusing on the single-task and multi-task design, reviews the recent literature on pain-related fNIRS research, in order to provide a reference for future research.