CT引导三叉神经半月节高电压与标准电压脉冲射频对三叉神经眼支受累的带状疱疹后遗神经痛的临床疗效[作者单位：272000，济宁医学院附属医院疼痛科 通讯作者：魏祥国：Email：[e-mail]]

The effect of CT-guided high voltage pulse and standard voltage pulse radiofrequency of trigeminal semilunar ganglion of postherpetic neuralgia with trigeminal involvement

摘要:

比较CT引导下三叉神经半月节高电压与标准电压脉冲射频治疗三叉神经眼支受累的带状疱疹后遗神经痛(PHN)的临床疗效。方法：选取三叉神经眼支受累的带状疱疹后遗神经痛患者60例，年龄52至76岁，男性20例，女性40例，随机分为两组，高电压组（H）与标准电压组（B）；记录两组患者治疗前、治疗后3d、1周、4周、8周、12周VAS，并记录VAS＜4分的例数；补救治疗次数≥2例数；8、12周时疗效评定及不良反应发生情况。结果：两组患者治疗后不同时间点VAS＜4分的例数较术前明显减少(P＜0.05)，差异有统计学意义。与标准脉冲组相比，高电压脉冲组在治疗后3d、1周、4周时VAS＜4分的例数无明显差异、而在8周、12周时VAS＜4分的例数明显增多（P＜0.05）；H组补救治疗例数较B组无统计学差异（P＞0.05）；H组治疗后8周、12周的疗效评定优于B组（P＜0.05）。结论：CT引导下三叉神经半月节高电压脉冲射频治疗三叉神经眼支受累的带状疱疹后遗神经痛安全有效，可应用于临床。比较CT引导下三叉神经半月节高电压与标准电压脉冲射频治疗三叉神经眼支受累的带状疱疹后遗神经痛(PHN)的临床疗效。方法：选取三叉神经眼支受累的带状疱疹后遗神经痛患者60例，年龄52至76岁，男性20例，女性40例，随机分为两组，高电压组（H）与标准电压组（B）；记录两组患者治疗前、治疗后3d、1周、4周、8周、12周VAS，并记录VAS＜4分的例数；补救治疗次数≥2例数；8、12周时疗效评定及不良反应发生情况。结果：两组患者治疗后不同时间点VAS＜4分的例数较术前明显减少(P＜0.05)，差异有统计学意义。与标准脉冲组相比，高电压脉冲组在治疗后3d、1周、4周时VAS＜4分的例数无明显差异、而在8周、12周时VAS＜4分的例数明显增多（P＜0.05）；H组补救治疗例数较B组无统计学差异（P＞0.05）；H组治疗后8周、12周的疗效评定优于B组（P＜0.05）。结论：CT引导下三叉神经半月节高电压脉冲射频治疗三叉神经眼支受累的带状疱疹后遗神经痛安全有效，可应用于临床。

Abstract:

[Abstract] Objective:To evaluate the effect of CT-guided high voltage pulse and standard voltage pulse radiofrequency of trigeminal semilunar ganglion of postherpetic neuralgia in the head and face. Methods 60 patients with postherpetic neuralgia in the head and face, aged 52-76 years, 20 males and 40 females, were randomly divided into two groups: high voltage group (H) and standard voltage group (B); VAS before treatment, 3 days, 1 week, 4 weeks, 8 weeks and 12 weeks after treatment were recorded in the two groups, the number of remedial treatment ≥ 2 cases. Efficacy evaluation and adverse reactions were observed after 8 weeks . Results: Compared with before treatment, the VAS scores of the two groups were significantly lower at 1 day, 1 week, 4 weeks and 8 weeks after treatment, the difference was statistically significant (P < 0.05); the number of remedial treatment cases in group H had no significant difference compared with in group B; no adverse reactions occurred in two groups. Conclusion: CT-guided is safe and effective to treat the postherpetic neuralgia of the head and face .