Abstract:Objective: To observe the clinical feasibility and efficacy of a novel approach of ultrasound-guided " two-points via one puncture " in blocking the posterior medial branch of lumbar spinal nerve. Methods: Forty patients were included to be treated with ultrasound-guided lumbar medial nerve block (LMBB). L4 and L5 MBB were adopted the " two-points via one puncture " approach. The total time to perform the unilateral L4 and L5 MBB and visual analogue scale (VAS) scores before treatment, 1 hour after treatment and 2 weeks after treatment were recorded. Overall effective response rate were calculated after a single treatment and at the end of the treatment course. Results: All the LMBB performances were successfully finished under the ultrasound guidance. The performance time of unilateral L4+L5MBB using “two-points via one puncture " approach was 276±61s. Compared with before treatment, VAS scores decreased significantly at 1 hour and 2 weeks after treatment (P<0.05), and the overall effective response rate of the total treatment course was 85%. Conclusion: The optimized ultrasound-guided " two-points via one puncture " approach of L4+L5MBB solves the difficulties encountered in the practice of ultrasound-guided L5MBB, ensures the effectiveness and safety of the treatment, and has a good clinical application prospect.