脉冲射频治疗颈段带状疱疹后神经痛的临床疗效观察

OBSERVATION CLINICAL OBSERVATION OF PULSE RADIOFREQUENCY TREATMENT FOR POST-HERPETIC NEURALGIA

摘要:

目的：探究脉冲射频(Pulse radiofrequency, PRF)治疗颈段带状疱疹后神经痛(postherpetic neuralgia, PHN)的临床疗效。方法：93例颈段PHN患者,随机分为药物治疗组(drug treatment group, group C)、神经阻滞组(nerve block group, group N)、脉冲射频组(pulsed radiofrequency group, group R),每组31例。记录患者治疗前及治疗后不同时间点的视觉模拟评分(Visual Analogue Scale, VAS),SF-MPQ、SRSS、SAS及SDS评分,总有效率及镇痛药物用量。结果：三组患者治疗后的疼痛评分均较之前有不同程度的降低,但脉冲射频治疗后,疼痛缓解持续时间更长,且镇痛药用量更少(P<0.05)。R、N组中睡眠及焦虑抑郁等状况较C组同期显著好转(P<0.05)。R、N和C组的总有效率分别为 93％,74％和26％。结论：脉冲射频、神经阻滞及口服药物治疗均能一定程度缓解疼痛,但PRF能够更早期减轻疼痛,有效率更高,持续时间更长,相关并发症(头晕、嗜睡、恶心等)的发生率也更低。

Abstract:

Objective:To investigate the clinical efficacy of pulse radiofrequency (PRF) in the treatment of postherpetic neuralgia (PHN).Methods:Ninety-three patients with cervical PHN who were admitted to the Department of Pain, Xuzhou Medical University Affiliated Hospital from 2018.01 to 2010.05 were randomly divided into drug treatment group (group C), nerve block group (group N),pulsed radiofrequency group (group R), 31 cases in each group. Visual analogue scale (VAS) and other related scales (SF-MPQ, SRSS, SAS, SDS) were recorded before treatment, 1 day, 1 week, 1 month, and 3 months after treatment. total effective treatment rate and remedial analgesic medication. Results:After treatment, the VAS scores of the three groups were lower than those before treatment, but in the R group, the pain relief lasted longer, and the R group and N patients had significantly less remedy for analgesia than C. Group (P < 0.05). In addition, the VAS, SF-MPQ, SRSS and other scales in the R and N groups were significantly lower than those in the C group (P<0.05). The total effective rates of the R, N, and C groups were 93%, 74%, and 26%, respectively. Conclusion: Pulsed radiofrequency, nerve block, and oral medication can alleviate pain in a certain degree, but PRF can relieve pain early, and can achieve a 50% pain relief in a higher percentage of patients, related complications (dizziness, The incidence of lethargy, nausea, etc. is also lower.