Abstract:Abstract Objective: by using the Regional Homogeneity method of resting brain functional magnetic resonance imaging (fmri),we investigate the central mechanism of cervicocogenic headache and the degree of change in the patient's brain area .Methods: GE 3.0T magnetic resonance imaging was used to perform resting functional magnetic resonance scanning for 13 patients with Cervicocogenic headache (CeH group) and13 healthy volunteers (health control group (HC group). After the use of post-processing software for data processing statistics.Correlation analysis was performed between Regional Homogeneity (ReHo) of different brain areas in the CeH group,visual analogue scale (VAS),and disease course. Results: Compared with HC group, the brain areas with increased ReHo value in CeH group were bilateral precuneus, left corpus callosum, left dorsal thalamus, left parahippocampal gyrus, right insula, right occipital middle gyrus, and bilateral cerebellar hemispheres. Brain regions with decreased ReHo were: bilateral superior frontal gyrus - middle frontal gyrus - anterior cingulate gyrus, right central posterior gyrus, right precuneus - posterior cingulate gyrus, right middle temporal gyrus, and left inferior occipital gyrus. In addition, there was no correlation between brain ReHo and VAS score and disease course in the CeH group.Conclusion: Cervicocogenic headache is a pathological state that affects multiple brain ,involving emotion, memory, cognitive and other aspects.
