脊髓电刺激治疗下肢缺血性疼痛的临床观察

CLINICAL OBSERVATION ON SPINAL CORD STIMULATION IN THE TREATMENT OF ISCHEMIC PAIN OF LOWER LIMBS

摘要:

目的：观察脊髓电刺激对下肢缺血性疼痛患者的治疗效果。方法：选取符合纳入排除标准的下肢缺血性疼痛患者19例，行脊髓电刺激治疗，对比患者治疗前与治疗后各时间点的视觉模拟评分 (visual analogue scale, VAS) 、匹兹堡睡眠质量指数 (pittsburgh sleep quality index, PSQI)，皮肤温差改变和不良反应。结果：19例患者中17例行发生器永久植入，电极置入后1 天、1 周、1个月、3个月、6个月的VAS评分较治疗前均有显著改善(P ＜0.05)；治疗后3个月和6个月时患者的PSQI与治疗前相比存在统计学差异(P＜ 0.05)；治疗前和治疗后1周体表温差显著下降（P＜0.05）；未观察到严重不良反应。结论：SCS可改善下肢缺血性疾病患者的疼痛、睡眠情况及下肢微循环，不良反应少，可安全有效的应用于临床。

Abstract:

Objective:To observe the therapeutic effect of spinal cord stimulation on ischemic pain of lower limbs.Methods:19 patients with ischemic pain of lower limbs who met the inclusion criteria were treated with spinal cord stimulation.Visual analogue scale (VAS), Pittsburgh sleep quality index (PSQI), skin temperature change and adverse reactions before and after treatment were compared.Results:Among 19 patients, 17 underwent generator implantation. VAS scores at 1 day, 1 week, 1 month, 3 months and 6 months after SCS were significantly decreased compared with those before treatment (P < 0.05). PSQI at 3 months and 6 months after treatment were significantly different from that before treatment (P < 0.05).Temperature difference of lower limbs decreased significantly at 1 week after treatment compared with those before treatment (P < 0.05).No serious adverse reactions were observed.conclusion: SCS can improve the pain, sleep and microcirculation of lower limbs in patients with ischemic diseases of lower limbs, with less adverse reactions, and can be safely and effectively applied in clinical practice.