抗病毒联合皮下及肋间神经阻滞治疗带状疱疹痛

EFFECT OF ANTIVIRAL THERAPY COMBINED WITH ANALGESICS FOR THE TREATMENT OF HERPES ZOSTER PAIN

摘要:

目的：观察抗病毒治疗联合镇痛药物治疗带状疱疹痛的临床效果.方法：60例胸部带状疱疹神经痛患者随机分为三组,A组：皮内注射消炎镇痛药＋抗病毒治疗;B组：肋间神经阻滞＋抗病毒治疗;C组：单纯抗病毒治疗.以视觉模拟评分（VAS）和睡眠质量评分（QS）评定治疗效果.结果：治疗后从即刻开始至观察期（30d）结束,A、B组VAS评分较治疗前显著降低（P＜0.01）,睡眠状况也明显改善（P＜0.01）;而C组患者仅在第14天开始疼痛有所减轻,睡眠状况好转.结论：采用皮内注射或肋间神经阻滞行镇痛治疗、联合抗病毒药物治疗对带状疱疹患者的疼痛缓解和睡眠质量改善有很好的疗效.

Abstract:

To observe effect of antiviral therapy combined with analgesic for the treatment of herpes zoster pain. Methods: Sixty persons suffering from herpes zoster were randomly divided into 3 groups: intradermal injection with antiviral therapy group(group A), intercostal nerve block group with antiviral therapy (group B), and simply antiviral therapy (group C). To evaluate the therapeutic efficacy, visual simulation score(VAS)and quality of sleep(QS) were used. Results: After treatment, the scores of VAS and QS in group A and B were lower than before (P<0.01);but group C was not significantly improved until two weeks after treatment. Conclusion: The clinical effect of local intradermal injection or intercostal nerve block combined with antiviral therapy is evident on relief of herpes zoster pain and improvement of sleep quality.