Abstract:Objective: To observe the effect and safety of different analgesic strategy on patients suffering from long-bone fracture. Methods: 174 patients in our hospital undergoing fracture in humerus, ulna, radius, femur, tibia or fibula from year 2002 to 2005 were involved in the study. The patients received different analgesic strategies in their first aid out of hospital and in the secondary medical care in the hospital. The changes of visual analogue score(VAS) and the satisfactory degree were recorded before and after analgesic treatment, respectively. Results: Patients with diazepam, bucinperazine or kitamin muscular injection out of hospital showed less pain and higher tolerance to pain maragement in the secondary medical care in the hospital. For the analgesic treatment in hospital, local nerve blockage was more effective than systemic administration of drugs. None of patients showed safety problem due to analgesic treatment. Conclusion: Appropriate analgesic treatment given as early as possible could help the patients safely pass the acute pain period and accept further treatment with less suffering.