经皮穿刺椎体成型术治疗椎体肿瘤及骨质疏松症

PERCUTANEOUS VERTEBROPLASTY FOR THE TREATMENT OF VERTEBRAL TUMOR AND OSTEOPOROSIS

摘要:

目的：探讨经皮穿刺椎体成型术治疗椎体肿瘤及骨质疏松症的临床应用价值。方法：对37例共59个椎体行经皮穿刺椎体成型术，其中血管瘤2例2个椎体、骨质疏松症11例16个椎体、椎体恶性肿瘤24例41个椎体。在X线定位下，将不透X线骨水泥（在骨水泥甲基丙烯酸树脂多聚体PMMA粉剂中加入2ml造影剂以透视显影）按粉剂与液体为3：2比例混合调制成糊状，用1ml注射器匀速缓慢注入病变椎体。结果：经皮穿刺椎体成型术后，脊柱CT和平片随访观察骨水泥密度、形态与术后所见无变化，未见椎体进一步压缩。止痛从注入骨水泥开始到术后7天显效，随访12个月。13例良性病变全部达到止痛效果，恶性肿瘤止痛效果达95．8％。本组没有发生并发症。结论：经皮穿刺椎体成型术适用于椎体血管瘤、骨质疏松症、转移瘤等溶骨性病变。

Abstract:

Objective: To investigate the clinical applications of percutaneous vertebroplasty(PVP).Methods: Thirty-seven patients underwent 59 PVP including 2 vertebral hemangiomas with 2 PVP,11 osteoporosis with 16 PVP,and 24 vertebral malignant tumors with 41 PVP.PVP was done with radiopaque bone cement under the X-ray.The ratio of powdery polymethl methacrylate to liquid methl methacrylate was 3:2.The ropy paste was mixed and slowly injected using 1 ml syringe.Results: The density and form of bone cement were unchanged on follow-up imaging.No further compression of vertebral body occurred.The analgesic effect occurred from finishing PVP to post-operation 7 days and followed-up 12 months.The analgesic effect was 100% in benign lesions and 95.8% in malignant tumors.Conclusion: PVP ive rate is an effective procedure for patients with vertebral bemangioma,vertebral osteoporosis,osteolytic metastases,and other osteolytic diseases.