Abstract:Objective:To evaluate the clinical application of collagenase discolysis in the treatment of cervical disc herniation. Method: Epidural catheter were placed at the anterior epidural cleft. Collagenase of 1800u was injected through the catheter. Results: The follow-up period was from 3 months to 5 years after the operation in 763 patients with cervical disc herniation. The rate of excellence and good was 90.56%. The rate of effectiveness was 97.38%. Conclusion: Under the monitoring of C-arm X-ray,patients with definite diagnosis and indications of the operation could be treated with this technique.