Abstract:Objective: To observe the clinical effects of combined antidepressant (Deanxit) and anticonvulsant on failed neuralgia. Method: The visual analog pain score (VAS) and Emotional Scale (ES) of the patients with failed trigeminal neuralgia were recorded before and after treatment. Result: Both VAS and ES were decreased significantly after combined medication. Conclusion: The combined medication may be an effective and safe treatment on failed trigeminal neuralgia.