头痛患者的电流感受阈值研究

STUDY OF CURRENT PERCEPTION THRESHOLD IN PATIENTS WITH HEADACHE

摘要:

目的：研究头痛患者头部位点的电流感受阈值(current perception threshold，CPT)变化，探讨电流感受阈值检测对头痛的辅助诊断意义。方法：头痛患者、正常对照各15人，对单侧耳前位点、乳突位点分别以2000Hz、250Hz、5Hz三种频率测定电流感受阈值，采用自动程序进行双盲检测，比较两组的异常率，将CFI、结果与影像学检查结果对比，分析头痛患者中器质性病变者与功能性头痛者的CPT结果差异。结果：头痛组与正常组CPT异常率分别为87％、26％，差异有显著意义。7名有器质性病变的头痛患者中有6名CPT结果异常，异常位点与受累的解剖结构具有一致性。所有受检者中4名CPT值增高者均证实有器质性病变。结论：头部位点各频率的CPT检测对头痛的定性有诊断价值，异常增高的CPT值提示头颈部器质性病变。

Abstract:

Objective: To demonstrate the CPT (current perception threshold) values of cranial sites and to study the diagnostic utility of CPT testing in patients with symptoms of headache. Methods: Fifteen patients with headache and 15 normal volunteers were given auto mode CPT test at trigeminal and C2 site. Three different frequencies of stimulation were used: 2000Hz, 250Hz and 5Hz. Automated double-blind mode was selected. Frequencies of abnormal CPT in two groups were compared. Result: Frequency of abnormality was 87% (13/15) and 26%(4/15) in headache group and normal control respectively. Six of seven patients who had organic disease showed abnormal CPT. And there was strong correlation between the sites of abnormal CPT and the brain structures that was involved. All the 4 patients who showed higher CPT were proved to have organic diseases. Conclusions: CPT allows for non-invasive quantitative and selective measurement of sensory nerve. CPT of trigeminal and C2 site is of great help in diagnosis of patients with headache.