康宁克通A,利多卡因复合用于胶原酶盘外溶解术

CLINICAL STUDY OF EXTRADISC INJECTION OF COLLAGENASE COMBINED WITH KENACORTA AND LIDOCAINE

摘要:

目的：观察康宁克通Ａ、利多卡因复合用于胶原酶盘外溶解术的作用。方法：随机将７０例患腰椎间盘突出症，经骶裂孔（硬膜外）前间隙置管注入胶原酶行盘外溶解术的患者分为三组，１、单纯胶原酶组（Ｃ组），２、胶原酶，利多卡因组（Ｃ＋Ｌ组）；３、胶原酶，康宁克通Ａ、利多卡因组（Ｃ＋Ｋ＋Ｌ组）。

Abstract:

Aim: To investigate the effect of extradisc injection of collagenase combined with kenacort A and lidocaine. 70 patients diagnosed lumbar disc herniation were randomly divided into three groups. 1. Group of collagenase(C group);2.Group of collagenase and lidocaine(C L group); 3. Group of collagenase, kenacortA and lidocaine.(C K L group). Result: The rate of pain decrease in C K L group was significantly higer than C group and C L group in 2 postoperative weeks. The rate of Straight Leg Rising in C K L group was significantly higher than C group in 2 postoperative weeks. In the postoperative 7th and 14th day, VAS of C K L group was significantly lower than C group and C L group. It is concluded that the combined use of kenacortA and lidocaine can effectively prevent postoperative pain of extradisc injection of collagenase. The extradisc injection of collagenase via the anterior epidural spase is an effective method for the treatment of lumbar disc herniation. Three month of postoperative pain assessment revealed that 81% of total groups obtained excellent or good results, the total effective rate was 97%,the excellent or good rate of C K L group was significantly higher than C group.