Abstract:Since 1994, 86 cases of lumbar intervertebral disc herniation have been treated by injection of collagenase. The injection was performed under local anestheda using image intensifier control (X-ray or ultra-sonography). Absolute tal rest and close othervation were required for 7 to 14 days after the injection. According to 4 Category grading, the excellent and gnd results were 90. 7%. There were no serious complication. The procedure is simple and safe and the results encouraging. It can be performed under the control by conventional X-ray or B-mode ultra-sonography. We consider that this treatment can be used in hoopitals of the grass-roots level.