口服曲马多用于痔结扎术超前镇痛的临床研究

THE CLINICAL STUDY OF PRE-EMPTIVE ANALGESIC EFFECT OF TRAMADOL

摘要:

选择痔结扎术患者６３例，随机分成Ａ、Ｂ两组。Ａ组３３例，术前３０分钟口服曲马多５０ｍｇ，胃复安１０ｍｇ；Ｂ组３０例为对照，术前未做处理。两组均施行简易骶管麻醉，单次注入１％利多卡因１５～１７ｍｌ，手术前再用０．７％利多卡因１０ｍｌ，１％亚甲蓝１ｍｌ做局部浸润麻醉，手术历时１０～２０分钟。骶麻后１小时及３小时，两组均再口服曲马多５０ｍｇ，胃复安１０ｍｇ各一次。试验结果镇痛强度Ａ组明显优于Ｂ组；镇痛持续时间Ａ组明显长于Ｂ组；患者对镇痛满意程度Ａ组大于Ｂ组；Ｂ组因疼痛引起尿潴留５例，Ａ组没有出现。结果表明；术前口服曲马多有较好的超前镇痛效应。

Abstract:

cases with hemorrhoid operation were randomly divided into two groups.Ingroup A oral administration of tramedol 50mg and metoclopremidom 10mg was given 30minutes before operation, while in group B none was given before operation as control.Thetwo groups were given caudsl analgesia in which they were injected 1% lidocainum 15-17ml,followed by local anesthesia in which they were injected 0.7% lidocainum 10 ml and 1% methylenum 1ml before operation.The eperation lasted 10-20 minutes. Both groupstook tramedol 50mg and metoclopramidum 10mg 1h and 3h after caudal analgesia.Results:The POSt operation analgesic intensity of group A was statistically stronger than group B(P<0.01);The postoperation analgesic duration of grouop A was statistically longer thangroup B(P<0.01).There were 16.6% patients having retention of urine in group Bwhile none in Group A.Rate of satisfaction was 97% in Group A and 30% in group B.The results suggested that taking tramedol orally before operation can produce effective pre emptive analgesin.